Dr. Lam Ho from Tuen Mun Hospital in Hong Kong used the 1st POT PTCA NC balloon on last Friday, 24th May 2024. This was a case of Left Main In-Stent Restenosis and Dr. Lam used a 4.5mm X 6mm POT balloon to treat the lesion. After the case, Dr. Lam satisfied the result and mentioned he will go for a series of cases to collect the experience for the benefit of POT balloon.